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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Trends Genet. 2020 Nov 14;37(5):433–443. doi: 10.1016/j.tig.2020.10.005

Figure 2.

Figure 2.

A compilation of germline variants associated with outcome discussed in this review shows that the absolute value of the natural log of the hazard ratio (HR) (effect size) is negatively correlated with the frequency of the alternate allele in the population.