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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Trends Genet. 2020 Nov 14;37(5):433–443. doi: 10.1016/j.tig.2020.10.005

Figure 3.

Figure 3.

The hallmarks of germline variants in cancer. The molecular mechanisms described in Figure 1 lead to larger phenotypic changes that drive the differences in clinical outcome.