Table 2.
Headache Related Measures
| Questionnaire | CM | PoTS-ALL | CM vs POTS-ALL p-value | PoTS-Mig | PoTS-NonMig | CM vs PoTS-Mig vs PoTS-NonMig p-value |
|---|---|---|---|---|---|---|
| N | 30 | 30 | 20 | 10 | ||
| Age of headache onset, years (median; IQR) | 15.5; 10 | 16.0; 13 | 0.42 ¥ | 14.5; 13 | 23.0; 9 | 0.66 † |
| Headache days per month (median; IQR) | 20; 15 | 14; 16 | 0.03 ¥ | 18; 17 | 10; 10 | 0.05† |
| Headache with activity, triggering or worsening (%) | 46% | 82% | 0.005 Δ | 93% | 44% | 0.01 ǂ |
| Orthostatic headache, headache induced by tilt table testing (%) | 17% | 48% | 0.02 Δ | 44% | 57% | 0.16 ǂ |
| HIT-6 Score, headache impact (mean; SD) | 63; 6 | 62; 12 | 0.23 ¥ | 63; 6 | 51; 12 | 0.0002† |
| MIDAS Score, headache related disability (median; IQR) | 41; 44 | 26; 42 | 0.13 ¥ | 47; 42 | 11; 22 | 0.05† |
| SF-PhotoQ, headache-associated photophobia symptoms (median; IQR) | 4; 1 | 4; 1 | 0.96 ¥ | 4; 1 | 3; 2 | 0.23† |
| ASC-12, headache-associated allodynia symptoms (median; IQR) | 5; 8 | 3.5; 8 | 0.90 ¥ | 7; 6 | 0; 3 | 0.04† |
| Headache associated craniofacial autonomic symptoms, # out of 8 (median; IQR) | 2; 3 | 1; 2 | 0.30 ¥ | 2; 3 | 0; 1 | 0.06† |
CM, chronic migraine; IQR, inter-quartile range; Mig, migraine; NonMig, non-migraine; PoTS, postural tachycardia syndrome; SD, standard deviation.
¥
Wilcoxon rank sum test (PoTS-All vs. CM comparison)
Δ
chi-square statistic (PoTS-All vs. CM comparison)
†
Kruskal-Wallis rank sum test (PoTS-Mig vs. PoTS-NonMig vs. CM comparison)
ǂ
chi-square statistic (PoTS-Mig vs. PoTS-NonMig. vs. CM comparison)