. Author manuscript; available in PMC: 2022 May 1.

Published in final edited form as: Anesthesiology. 2021 May 1;134(5):784–791. doi: 10.1097/ALN.0000000000003700

Table 1.

Summary of data from two meta-analysis of randomized controlled studies of near infrared spectroscopy monitoring interventions in surgical patients. The data are listed as relative risk (RR, 95% confidence intervals). The number (N) of subjects evaluated for each outcome and the number (N) of randomized controlled trials evaluated are given for each publication.

	Stroke	Delirium	Delayed Neurocognitive Recovery	Acute Kidney Injury	Blood Transfusion	Length of stay in the ICU	Hospital length of stay	Mortality (within 30 days)
Serraino & Murphy²⁹
RR (95% CI)	1.08^‡ (0.40 to 2.91)	Meta-analysis not performed due to heterogeneity between trials		0.88^‡ (0.52, 1.49)	0.93^† (0.77, 1.12)	0^‡ (−0.44, 0.44)	−0.45^† (−0.90, 0.01)	0.76^† (0.30, 1.96)
N	1138			1043	744			608
N of trials	7			6	4			4
Cochrane Review³⁰
RR (95% CI)	0.25^† (0.03, 2.20)	0.63^† (0.27,1.45)	0.62* (0.37, 1.04)	0.93^† (0.77, 1.12)				0.63^† (0.08, 5.03)
N	240	190	962	744				390
N of trials	2	1	6	4				3

Note: The strength of the evidence for each outcome was rated as *moderate; ^†low; or ^‡very low.