Table 1:
Group means (SD) and omnibus test results of clinical and demographic characteristics. ANOVA analyses were used to compare all measures between groups except sex ratio, where a chi-squared test was used. MRI: Magnetic resonance imaging, BNT: Boston Naming Test, PPT: Pyramids and Palm Trees Test, PBAC: The Philadelphia Brief Assessment of Cognition (0=most apathetic, 4=least apathetic). Numbers in square brackets are Ns when less than the total.
| control (N=37) | bvFTD (N=74) | naPPA (N=22) | svPPA (N=42) | Group comparisons | ||
|---|---|---|---|---|---|---|
| Sex | Female (N, percent) | 24 (64.9%) | 26 (35.1%) | 11 (50%) | 23 (54.8%) | χ=9.9, p=0.019 |
| Male (N, percent) | 13 (35.1%) | 48 (64.9%) | 11 (50%) | 19 (45.2%) | ||
| Education | 15.9 (2.5) | 15.8 (2.8) | 15.3 (3.1) | 15.1 (2.8) | F(3,171)=0.9, p=0.437 | |
| Age (years) | 68.5 (7.9) | 63.1 (8.7) | 70.4 (9.4) | 63.3 (7) | F(3,171)=7.3, p<0.001 | |
| Disease duration (years) | - | 4.4 (3.5) | 3.2 (1.9) | 3.9 (2) | F(2,135)=1.5, p=0.239 | |
| Time between MRI & picture description recording (months) | - | [42] | [8] | [26] | F(2,73)=1.1, p=0.326 | |
| - | 2.2 (1.9) | 1.7 (1.7) | 2.8 (2.6) | |||
| Mini mental state exam (0–30) | [31] | [68] | [20] | [38] | F(3,153)=12.1, p<0.001 | |
| 29.2 (1) | 23.6 (5.5) | 22.7 (6) | 22.1 (6.3) | |||
| BNT (0–30) | [23] | [68] | [16] | [40] | F(3,143)=99.8, p<0.001 | |
| 27.9 (2.5) | 23.8 (5.8) | 24.7 (4.6) | 7.5 (6.4) | |||
| Animals and Tools (Max 60 sec) | [23] | [65] | [16] | [39] | F(3,139)=30.8, p<0.001 | |
| 16.8 (4.6) | 9.2 (5.2) | 8.2 (4.4) | 5.1 (3.8) | |||
| PPT (0–52) | [18] | [35] | [7] | [19] | F(3,75)=11.4, p<0.001 | |
| 50.8 (1.9) | 42.9 (7.9) | 48.4 (2.9) | 39.6 (6.6) | |||
| PBAC Apathy (0–4): N | [6] | [62] | [14] | [37] | F(3,115)=2.88, p=0.039 | |
| 3.3 (0.5) | 2.1 (1.1) | 2.7 (1.2) | 2.5 (1.2) | |||