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. 2021 Apr 13;12:2193. doi: 10.1038/s41467-021-22497-2

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Motif-swapped and selected individual mutant module lysates were incubated with 300 μM each of 1, 2a, 2b, 2c, and 2d, simultaneously. Products were analyzed by HR-LC-MS, and the product distributions are shown. Error bars are the standard deviation (n = 3 biological replicates) of the mean. Individual replicates are shown as circles. Source data are provided as a Source Data file.