Table 1.
Clinical data of mothers and infants recruited.
| Infants (n = 27) | Mothers (n = 26) | P value | |
|---|---|---|---|
| Sex | |||
| Male, n (%) | 12 (44.4) | / | |
| Female, n (%) | 15 (57.7) | / | |
| Median GA, weeks (range) | 38.6 (31+6 ~ 41+1) | ||
| < 37w, n (%) | 6 (22.2) | / | |
| ≥ 37w, n (%) | 21 (80.8) | / | |
| Median birth weight, g (range) | 2880 (1490 ~ 3850) | / | |
| < 2500 g, n (%) | 7 (25.9) | / | |
| ≥ 2500 g, n (%) | 20 (74.1) | / | |
| Apgar score < 7 at 1.5 min, n (%) | 0 (0), 0 (0) | / | |
| Delivery mode | |||
| Eutocia, n (%) | 4 (14.8) | 4 (15.4) | |
| Cesarean, n (%) | 23 (85.2) | 22 (84.6) | |
| Median age, years (range) | / | 31 (22 ~ 41) | |
| With symptom of COVID-19, n (%) | 0 (0) | 13 (50.0) | |
| CT scan with viral pneumonia, n (%) | 0 (0) | 23 (88.4) | |
| SARS-CoV-2 nucleic acid (+), n (%) | 0 (0) | 9 (34.6) | |
| GAO | |||
| < 28w | / | 5 (19.2) | |
| ≥ 28w | / | 21 (80.8) | |
| Anti-SARS-CoV-2 IgG and IgM | |||
| IgM(−)/IgG (−),n (%) | 15 (55.6) | 5 (19.2) | 0.0103 |
| IgM (+)/IgG (−),n/N (%) | 0 (0) | 0 (0) | |
| IgM (−)/IgG ( +),n/N (%) | 12 (44.4) | 7 (26.9) | 0.2492 |
| IgM (+)/IgG (+),n/N (%) | 0 (0) | 14 (53.8) | < 0.0001 |
| Total IgM ( +) | 0 (0) | 14 (53.8) | < 0.0001 |
| Total IgG ( +) | 12 (44.4) | 21 (80.8) | 0.0244 |
| IgG positive rate (%) | |||
| DMOD ≤ 14d, n/N (%) | 3/16 (18.8)* | 10/15 (66.7) | 0.0113 |
| DMOD > 14d, n/N (%) | 9/11 (81.8)** | 11/11 (100) | 0.4762 |
| GAO < 28w, n/N (%) | 3/5 (60.0) | 5/5 (100) | 0.4444 |
| GAO ≥ 28w, n/N (%) | 9/22 (40.9) | 16/21 (76.2) | 0.0305 |
Between * and **, p value = 0.002.
n/N number of positive or negative cases/number of test cases, CT computed tomography, DMOD days from mother's onset to delivery, GAO gestational age at onset, GA gestational age.