Fig. 2. Characteristics of the panels for TMB prediction.

a Size (in Mb). The red line indicates the size of the FO-panel. The center line in the boxes corresponds to the median, the bounds of the boxes to the first and third quartiles, and the whiskers extend to the largest and lowest values no further than 1.5 times the inter-quartile range. Data beyond the end of the whiskers are called “outlying” points and plotted individually. b R² and RSE of the panels vs. size (in Mb). Only 4 representative cancer types are shown; breast carcinoma, colorectal carcinoma, melanoma, and non-small cell lung carcinoma (for other tumors, see Supplementary Fig. 4). The red line indicates the size of the FO-panel. Each dot represents a model, colors indicate initial datasets.