Table 1.
Comparing the patients’ baseline characteristics according to radiotherapy status.
| Variables | Before PSM | After PSM | ||||
|---|---|---|---|---|---|---|
| Non-RT | RT | P-value | Non-RT | RT | P-value | |
| 47,940 (100%) | 37,046 (100%) | 28,630 (100%) | 28,630 (100%) | |||
| Sex | < .0001 | < .0001 | ||||
| Male | 29,163 (60.83%) | 20,096 (54.25%) | 17,236 (60.20%) | 16,559 (57.84%) | ||
| Female | 18,777 (39.17%) | 16,950 (45.75%) | 11,394 (39.80%) | 12,071 (42.16%) | ||
| 28,630 | 28,630 | |||||
| Age, mean ± SD (year) | 63.48 ± 11.20 | 59.35 ± 11.13 | < .0001 | 61.83 ± 10.95 | 60.61 ± 10.96 | < .0001 |
| 20 ~ 29 | 257 (0.54%) | 198 (0.53%) | 122 (0.43%) | 140 (0.49%) | ||
| 30 ~ 39 | 1271 (2.65%) | 1660 (4.48%) | 835 (2.92%) | 1032 (3.60%) | ||
| 40 ~ 49 | 4407 (9.19%) | 5270 (14.23%) | 3104 (10.84%) | 3529 (12.33%) | ||
| 50 ~ 59 | 9860 (20.57%) |
10,788 (29.12%) |
7147 (24.96%) | 7589 (26.51%) | ||
| 60 ~ 69 | 14,958 (31.20%) | 11,544 (31.16%) | 9650 (33.71%) | 9461 (33.05%) | ||
| 70 ~ | 17,187 (35.85%) | 7586 (20.48%) | 7772 (27.15%) | 6879 (24.03%) | ||
| Medical aid beneficiarya | 4177 (8.71%) | 2127 (5.74%) | < .0001 | 1857 (6.49%) | 1854 (6.48%) | 0.9594 |
| Medial facilityb | < .0001 | < .0001 | ||||
| Tertiary hospital | 15,359 (32.04%) | 17,343 (46.81%) |
11,133 (38.89%) |
12,173 (42.52%) | ||
| General hospital | 4800 (10.01%) | 3016 (8.14%) | 2608 (9.11%) | 2498 (8.73%) | ||
| Hospital | 27,747 (57.88%) | 16,682 (45.03%) | 14,887 (52.00%) | 13,954 (48.74%) | ||
| Clinic | 34 (0.071%) | 5 (0.01%) | 2 (0.01%) | 5 (0.02%) | ||
| Primary cancer | ||||||
| Head and neck | 834 (1.74%) | 755 (2.04%) | 0.0015 | 675 (2.36%) | 682 (2.38%) | 0.8475 |
| Esophagus | 505 (1.05%) | 517 (1.40%) | < .0001 | 432 (1.51%) | 438 (1.53%) | 0.8376 |
| Stomach | 3648 (7.61%) | 1083 (2.92%) | < .0001 | 970 (3.39%) | 1064 (3.72%) | 0.0338 |
| Colorectal | 3784 (7.89%) | 3563 (9.62%) | < .0001 | 2875 (10.04%) | 3108 (10.86%) | 0.0015 |
| Liver | 2774 (5.79%) | 1986 (5.36%) | 0.0075 | 1783 (6.23%) | 1805 (6.30%) | 0.7044 |
| Hepatobiliary | 693 (1.45%) | 314 (0.85%) | < .0001 | 317 (1.11%) | 306 (1.07%) | 0.6577 |
| Pancreas | 1222 (2.55%) | 569 (1.54%) | < .0001 | 494 (1.73%) | 534 (1.87%) | 0.2081 |
| Pharynx | 203 (0.42%) | 232 (0.63%) | < .0001 | 180 (0.63%) | 194 (0.68%) | 0.4677 |
| Lung | 24,170 (50.42%) | 21,197 (57.22%) | < .0001 | 18,481 (64.55%) | 17,760 (62.03%) | < .0001 |
| Breast | 3355 (7.00%) | 6463 (17.45%) | < .0001 | 3248 (11.34%) | 3898 (13.62%) | < .0001 |
| Cervix | 308 (0.64%) | 615 (1.66%) | < .0001 | 298 (1.04%) | 422 (1.47%) | < .0001 |
| Uterine | 153 (0.32%) | 235 (0.63%) | < .0001 | 139 (0.49%) | 186 (0.65%) | 0.0089 |
| Ovary | 676 (1.41%) | 461 (1.24%) | 0.0371 | 394 (1.38%) | 421 (1.47%) | 0.3408 |
| Prostate | 1551 (3.24%) | 1011 (2.73%) | < .0001 | 1036 (3.62%) | 951 (3.32%) | 0.0523 |
| Scrotum | 59 (0.12%) | 35 (0.09%) | 0.2137 | 33 (0.12%) | 32 (0.11%) | 0.9012 |
| Kidney | 920 (1.92%) | 886 (2.39%) | < .0001 | 696 (2.43%) | 768 (2.68%) | 0.0566 |
| Bladder | 543 (1.13%) | 322 (0.87%) | 0.0001 | 310 (1.08%) | 300 (1.05%) | 0.684 |
| Thyroid | 972 (2.03%) | 752 (2.03%) | 0.9806 | 582 (2.03%) | 660 (2.31%) | 0.0252 |
| Operation | 1208 (2.52%) | 2571 (6.94%) | < .0001 | 1091 (3.81%) | 1641 (5.73%) | < .0001 |
| Chemotherapy | 16,871 (35.19%) | 21,323 (57.56%) | < .0001 | 13,731 (47.96%) | 14,798 (51.69%) | < .0001 |
| Diagnostic year | < .0001 | < .0001 | ||||
| 2005 | 3896 (8.13%) | 1804 (4.87%) | 1732 (6.05%) | 1564 (5.46%) | ||
| 2006 | 4825 (10.06%) | 2191 (5.91%) | 2007 (7.01%) | 1901 (6.64%) | ||
| 2007 | 4837 (10.09%) | 2297 (6.20%) | 2146 (7.50%) | 2043 (7.14%) | ||
| 2008 | 4226 (8.82%) | 2476 (6.68%) | 2197 (7.67%) | 2045 (7.14%) | ||
| 2009 | 4090 (8.53%) | 2754 (7.43%) | 2323 (8.11%) | 2289 (8.00%) | ||
| 2010 | 4210 (8.78%) | 3088 (8.34%) | 2532 (8.84%) | 2436 (8.51%) | ||
| 2011 | 3691 (7.70%) | 3280 (8.85%) | 2453 (8.57%) | 2587 (9.04%) | ||
| 2012 | 3427 (7.15%) | 3552 (9.59%) | 2474 (8.64%) | 2461 (8.60%) | ||
| 2013 | 3568 (7.44%) | 3859 (10.42%) | 2656 (9.28%) | 2616 (9.14%) | ||
| 2014 | 3550 (7.41%) | 4005 (10.81%) | 2573 (8.99%) | 2871 (10.03%) | ||
| 2015 | 3566 (7.44%) | 4010 (10.82%) | 2683 (9.37%) | 2810 (9.81%) | ||
| 2016 | 4054 (8.46%) | 3730 (10.07%) | 2854 (9.97%) | 3007 (10.50%) | ||
| CCI | 4.53 ± 2.41 | 4.92 ± 2.10 | < .0001 | 4.86 ± 2.34 | 4.91 ± 2.14 | < .0001 |
Non-RT Non-radio therapy, RT radio therapy, PSM propensity score matching, CCI Charlson Comorbidity Index.
aRecipients received in the form of public assistance to guarantee the minimum standard of healthcare insurance in Korea.
bFour different classification of hospitals in Korea25.