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Regulation of metabolism in TFH cell differentiation. Basic processes and correlations of glucose, lipid and amino acid metabolism. mTOR signalling and transcription factors such as Myc and HIF1α promote TFH cell differentiation related to improvements in metabolism. The differentiation of TFH cells is inhibited by the glycolysis inhibitors 2‐DG and succinate, a substrate of oxidative phosphorylation.
