Table 3.
Breakdown of patients with FIGO score 7 and treatment outcomes
| Age (years) | Initial hCG value IU/l | Number of metastases | Size of uterine mass | Cycles of MTX | Outcome | Notes |
|---|---|---|---|---|---|---|
| 45 | 101 563 | 0 | >5 cm | 8 | Cured on MTX alone | Advised high risk but patient chose MTX/FA |
| 31 | 30 782 | >8 | 3-5 cm | 7 | Switched to ActD and cured | Advised high risk but patient wanted MTX/FA and upon MTX-R insisted on ActD |
| 18 | 158 000 | 1 | >5 cm | 1 | Switch to EMA/CO | Initial score 6 as CXR report normal but MDT noted lung metastasis so upgraded to FIGO 7, switched to EMA/CO |
| 46 | 184 951 | 0 | >5 cm | 1 | Switch to EMA/CO | Initial score 6 in error but post-MDT review scored 7 switched to EMA/CO |
| 28 | 142 552 | 1 | >5 cm | 7 | Switch to EMA/CO | CXR reported as suspicious so FIGO 7, later CT chest normal so downgraded to FIGO 6 and continued MTX/FA |
ActD, actinomycin D; CT, computer tomography scan; CXR, chest X-Ray; EMA/CO, etoposide; hCG, human chorionic gonadotrophin; MDT, multi-disciplinary team meeting; MTX, methotrexate; MTX/FA, methotrexate and folonic acid; MTX-R, methotrexate resistance.