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. 2021 Mar 29;21:399–412. doi: 10.1016/j.omtm.2021.03.020

Figure 3.

Figure 3

Kinetics of luciferase expression in animals injected with the different amplicon vectors

(A–C) Time course of the BLI signal in mice injected with low titer (light blue) or high titer (dark blue) vAm-IE4/5-LiG2 (A); low titer (light green) or high titer (dark green) vAm-ECBA-LiG2 (B); low titer vAm-ESyn-LiG2 (red) or low titer vSAm-ESyn-LiG2 (purple) (C). (D and E) A comparison of the BLI signals produced by injection of the different amplicon vectors at the earliest (1 dpi, D) and latest (6 mpi, E) time points. 14 animals were injected with either low or high titer vAm-IE4/5-LiG2 vector, of which 8 were killed at 4 dpi, and 6 at 14 dpi. 28 animals per group were injected with other vectors, of which 16 were killed after at 4 dpi, 6 at 2 mpi, and 6 at 6 mpi. Therefore, data in (D) are the means ± SEM of 14 low or high titer vAm-IE4/5-LiG2 injected-mice and 28 animals of the other groups; data in (E) are the means ± SEM of 6 animals per group (but vAm-IE4/5-LiG2 injected-mice were not determined, n.d.). ∗∗p < 0.01; ∗∗∗p < 0.001; Mann-Whitney U test.