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. 2021 Mar 31;12:641436. doi: 10.3389/fphar.2021.641436

FIGURE 2.

FIGURE 2

Dose-dependent function of the (pooled,%) placebo response in a meta-analysis of randomized and placebo-controlled trials (RCT) in ulcerative colitis (22): the number of doctor visits during the trial has an effect on all clinical outcome parameters, clinical benefit (improvement), endoscopically assessed remission, histologically assessed remission, and clinical remission measures.