Table 1.
Sample characteristics gender-specific quartiles of uric acids among participants attending Qatar Biobank Study (N = 2981).
| Total | Q1 | Q2 | Q3 | Q4 | p-value | |
|---|---|---|---|---|---|---|
| N = 2,981 | N = 759 | N = 744 | N = 743 | N = 735 | ||
| Age (years) | 36.4 (11.1) | 34.9 (10.7) | 35.7 (10.7) | 36.3 (11.0) | 38.6 (11.6) | <0.001 |
| Sex (%) | 1.00 | |||||
| Men | 1,430 (48.0%) | 362 (47.7%) | 359 (48.3%) | 355 (47.8%) | 354 (48.2%) | |
| Women | 1,551 (52.0%) | 397 (52.3%) | 385 (51.7%) | 388 (52.2%) | 381 (51.8%) | |
| Smoking (%) | 0.38 | |||||
| Non-smoker | 2,022 (67.8%) | 491 (64.7%) | 507 (68.1%) | 511 (68.8%) | 513 (69.8%) | |
| Ex-smoker | 189 (6.3%) | 54 (7.1%) | 52 (7.0%) | 42 (5.7%) | 41 (5.6%) | |
| Current smoker | 770 (25.8%) | 214 (28.2%) | 185 (24.9%) | 190 (25.6%) | 181 (24.6%) | |
| Uric acid (µmol/L) | 296.53 (81.89) | 222.59 (52.09) | 272.40 (50.16) | 312.00 (54.87) | 381.69 (71.30) | <0.001 |
| BMI (kg/m2) | 28.4 (5.9) | 25.9 (5.2) | 27.2 (5.2) | 29.1 (5.4) | 31.6 (6.0) | <0.001 |
| Alkaline phosphatase (U/L) | 68.76 (19.91) | 65.69 (21.45) | 66.42 (17.01) | 71.35 (20.92) | 71.68 (19.21) | <0.001 |
| Calcium (mmol/L) | 2.28 (0.08) | 2.27 (0.08) | 2.28 (0.07) | 2.28 (0.08) | 2.29 (0.08) | <0.001 |
| Phosphorus (mmol/L) | 1.15 (0.17) | 1.16 (0.17) | 1.15 (0.16) | 1.15 (0.16) | 1.15 (0.17) | 0.72 |
| Dihydroxyvitamin D (ng/mL) | 18.67 (11.57) | 18.33 (11.69) | 18.31 (10.23) | 18.83 (11.52) | 19.22 (12.73) | 0.38 |
| eGFR (mL/min/1.73m2) | 111.35 (15.07) | 115.20 (13.79) | 112.45 (14.65) | 111.19 (14.01) | 106.42 (16.41) | <0.001 |
| eGFR< 90 mL/min/1.73m2 (%) | 256 (8.6%) | 40 (5.3%) | 50 (6.7%) | 54 (7.3%) | 112 (15.3%) | <0.001 |
| Estradiol (pmol/L) | 237.76 (283.47) | 275.70 (326.71) | 252.26 (300.27) | 225.26 (261.94) | 195.93 (226.65) | <0.001 |
| Free Thyroxin (pmol/L) | 13.18 (1.59) | 13.17 (1.52) | 13.28 (1.71) | 13.12 (1.57) | 13.16 (1.55) | 0.25 |
| Free triiodothyronine (pmol/L) | 4.43 (0.61) | 4.37 (0.57) | 4.46 (0.66) | 4.44 (0.64) | 4.45 (0.56) | 0.022 |
| Thyroid Stimulating Hormone (mIU/L) | 1.61 (1.15) | 1.53 (0.92) | 1.60 (1.18) | 1.70 (1.38) | 1.62 (1.05) | 0.047 |
| Bone mineral density (BMD) score (g/cm2) | ||||||
| Total body | 1.21 (0.13) | 1.18 (0.13) | 1.20 (0.13) | 1.21 (0.12) | 1.24 (0.15) | <0.001 |
| Hip trochanter | 0.82 (0.14) | 0.79 (0.14) | 0.81 (0.14) | 0.83 (0.13) | 0.86 (0.14) | <0.001 |
| Trunk | 1.00 (0.12) | 0.98 (0.12) | 1.00 (0.12) | 1.01 (0.11) | 1.03 (0.12) | <0.001 |
| Femoral upper neck | 0.85 (0.16) | 0.83 (0.16) | 0.84 (0.16) | 0.85 (0.16) | 0.87 (0.17) | <0.001 |
| Ward’s triangle | 0.83 (0.16) | 0.81 (0.16) | 0.83 (0.16) | 0.84 (0.16) | 0.86 (0.17) | <0.001 |
| Pelvis | 1.01 (0.13) | 0.99 (0.14) | 1.00 (0.13) | 1.01 (0.12) | 1.04 (0.14) | <0.001 |
| Lumber spine | 1.11 (0.14) | 1.08 (0.15) | 1.11 (0.14) | 1.12 (0.13) | 1.15 (0.14) | <0.001 |
Data are presented as mean (SD) for continuous measures, and n (%) for categorical measures.