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. 2021 Mar 31;12:653972. doi: 10.3389/fendo.2021.653972

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Copyright © 2021 Ke, Luan, Wu, Zhu and Tong

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Metabolic genes regulated by Mondo family. Metabolic genes regulated by MondoA and ChREBP at the transcriptional level are herein summarized. They are involved in glucose and fructose uptake, glycolysis, fructose metabolism, glycogenesis, hexosamine biosynthesis pathway (HBP), pentose phosphate pathway (PPP), and lipogenesis. MondoA targets are highlighted in red, ChREBP targets in green, and their common targets are in blue. HK II, hexokinase II; PTG, glycogen targeting protein; G6PDH, glucose-6-phosphate dehydrogenase; KHK, fructokinase; GFPT, glutamine:fructose-6-phosphate aminotransferase; PFKFB3, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3; TKT, transketolase; PK, pyruvate kinase; PDH, pyruvate dehydrogenase; SDHAP3, succinate dehydrogenase complex flavoprotein subunit A pseudogene 3; DCT, C4-dicarboxylate transport protein; ME1, malic enzyme; MOGAT2, monoacylglycerol O-acyltransferase 2; DGAT, diacylglycerol acyltransferase.