Table 4. Comparison of TMB adjusted for presence of oncogene.
Treatment-Naïve Samples | Treatment-Experienced Samples | Adjusted P value | |
---|---|---|---|
All oncogenes wild type | |||
n | 707 | 119 | 0.124 |
TMB median (mut/Mb) | 9 | 9 | |
Any oncogene mutated | |||
n | 108 | 36 | 0.836 |
TMB median (mut/Mb) | 4.5 | 4 |
Oncogenes included in analysis are EGFR, ALK, ROS1, BRAF, RET, and NTRK. P values were assessed with Wilcoxon rank-sum test and adjusted for multiple testing.