Table 1.
Characteristics of people with adult-onset Still’s disease (AOSD) and those with sepsis and healthy controls included in this study.
| Characteristics | Active AOSD | Inactive AOSD | Sepsis | HC |
|---|---|---|---|---|
| Age, mean (range) | 34.8(19-59) | 35.1(22-56) | 57.6(19-80) | 31.8(20-54) |
| Gender (female/male) | 15/5 | 9/1 | 23/6 | 23/7 |
| Laboratory values, mean ± SEM | ||||
| WBC (109/L) | 13.9 ± 2.0 | 10.9 ± 1.2 | 14.7 ± 2.1 | / |
| N (109/L) | 11.0 ± 2.0 | 8.0 ± 1.1 | 11.7 ± 1.5 | / |
| Platelets (109/L) | 274.7 ± 37.8 | 248.0 ± 14.1 | 172.9 ± 19.7 | / |
| Lymphocyte (109/L) | 2.2 ± 0.4 | / | 0.9 ± 0.1 | / |
| Hemoglobin (g/L) | 108.1 ± 4.2 | 133.0 ± 5.0 | 88.9 ± 3.8 | / |
| ALT (IU/L) | 187.8 ± 115.9 | 17.5 ± 3.3 | 49.0 ± 9.7 | / |
| AST (IU/L) | 82.3 ± 28.6 | 16.0 ± 1.0 | 67.6 ± 15.0 | / |
| Creatinine (umol/L) | 56.8 ± 3.3 | 77.1 ± 8.9 | 151.9 ± 32.9 | / |
| Urea (mmol/L) | 4.1 ± 0.4 | / | 11.7 ± 1.7 | / |
| CRP (mg/L) | 37.7 ± 14.8 | 1.7 ± 0.6 | 149.8 ± 18.3 | / |
| PCT (ng/ml) | / | / | 27.1 ± 9.8 | / |
| ESR (mm/h) | 42.5 ± 8.3 | 8.1 ± 1.8 | / | / |
| Lactate (mmol/L) | / | / | 3.2 ± 0.5 | / |
| Ferritin (ng/ml) | 4587.1 ± 1555.6 | 82.1 ± 28.2 | / | / |
| AOSD Parameters | ||||
| Fever | 15(75.0%) | 0(0) | / | / |
| Sore throat | 16(80.0%) | 0(0) | / | / |
| Evanescent rash | 14(70.0%) | 0(0) | / | / |
| Arthralgia | 15(75.0%) | 0(0) | / | / |
| Pneumonia | 3(15.0%) | 3(30.0%) | / | / |
| Pericarditis | 1(5.0%) | 0(0) | / | / |
| Hepatomegaly | 1(5.0%) | 1(10.0%) | / | / |
| Splenomegaly | 6(30.0%) | 2(20.0%) | / | / |
| Lymphadenopathy | 11(55%) | 3(30.0%) | / | / |
| Myalgia | 9(45.0%) | 2(20.0%) | / | |
| Pleurisy | 3(15.0%) | 0(0) | / | / |
| Weight loss | 4(20.0%) | 1(10.0%) | / | / |
| Stomach ache | 1(5.0%) | 0(0) | / | / |
| Renal dysfunction | 0(0) | 0(0) | / | / |
| Site of infection, n (%) | ||||
| Lung | / | / | 7(24.1%) | / |
| Abdominal | / | / | 22(75.9%) | / |
| Blood | / | / | 12(41.4%) | / |
| Others | / | / | 6(20.7%) | / |
| 28-day mortality, n (%) | / | / | 2(6.7%) | / |
Data are presented as n (percentages), mean ± SEM
APACHE II, Acute Physiology and Chronic Health Evaluation II; CRP, C‐reactive protein; n, numbers; SEM, mean ± standard error of mean; SOFA, Sequential Organ Failure Assessment; WBC, white blood cell count.