Table 1.

General physiological data in C57BL/6 mice.

		Food intake (g/24h)	Urine volume (ml/24 h)	Urine osmolality (mosmol/kg·H2O)	Plasma osmolality (mosmol/kg·H2O)	Δ Body weight (g)
Control		4.50 ± 0.09	1.27 ± 0.18	1426.67 ± 76.98	315.67 ± 1.23	0.31 ± 0.33
WD	24 h	2.82 ± 0.04**	0.96 ± 0.06	3051.67 ± 67.30**		-0.03 ± 0.31
	48 h	1.96 ± 0.09**	0.48 ± 0.10**	3711.67 ± 72.70***	328.20 ± 1.72***	-1.37 ± 0.26**
WD + Apelin-13	24 h	2.83 ± 0.04**	1.06 ± 0.07	2945.00 ± 50.32**		-0.40 ± 0.21*
	48 h	1.92 ± 0.03**	0.47 ± 0.08**	3398.33 ± 60.11***#	335.80 ± 2.98***#	-1.65 ± 0.23**

^*p < 0.05;

^**p < 0.01;

^***p < 0.001 vs. Control;

^#p < 0.05 vs. WD-48h.