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. 2021 Mar 31;12:661160. doi: 10.3389/fendo.2021.661160

Table 4.

Risk of metabolic syndrome associated with TSH levels in the euthyroid group.

TSH level (mIU/L) 0.27-1.25 1.25-2.23 2.23-3.21 3.21-4.20
Men
Abdominal obesity 1.216 (0.916,1.615) 1.054 (0.921,1.205) 0.965 (0.818,1.139) 1.010 (0. 803,1.270)
1.196 (0.876,1.634) 1.036 (0.893,1.202) 1.010 (0.843,1.211) 1.037 (0.805,1.337)
Hypertriglyceridemia 1.143 (0.851,1.535) 1.056 (0.921,1.212) 0.906 (0.766,1.073) 1.065 (0.845,1.342)
1.011 (0.738,1.385) 1.074 (0.926,1.247) 0.916 (0.763,1.099) 1.071 (0.830,1.382)
Low HDL-C 1.517 (0.976,2.358) 1.062 (0.885,1.275) 0.890 (0.711,1.115) 0.948 (0.704,1.277)
1.287 (0.816,2.032) 1.065 (0.883,1.285) 0.908 (0.720,1.145) 1.919 (0.676,1.249)
Hypertension 0.993 (0.755,1.305) 1.033 (0.906,1.177) 1.108 (0.944,1.301) 1.058 (0.846,1.323)
1.207 (0.895,1.627) 1.068 (0.927,1.229) 1.179 (0.991,1.402) 0.958 (0.753,1.218)
Hyperglycaemia 0.814 (0.617,1.068) 1.005 (0.881,1.147) 0.980 (0.832,1.153) 1.124 (0.897,1.408)
0.902 (0.669,1.217) 1.048 (0.906,1.213) 1.025 (0.857,1.226) 0.992 (0.775,1.270)
Metabolic syndrome 1.285 (0.948,1.740) 1.003 (0.870,1.156) 0.934 (0.784,1.112) 0.969 (0.764,1.231)
1.398 (1.025,1.907)* 1.047 (0.905,1.212) 0.966 (0.807,1.157) 0.898 (0.701,1.149)
Women
Abdominal obesity 0.654 (0.476,0.897)** 0.999 (0.850,1.175) 1.121 (0.940,1.336) 1.485 (1.189,1.854)**
0.960 (0.668,1.379) 1.044 (0.870,1.252) 1.080 (0.889,1.312) 1.532 (1.193,1.967)**
Hypertriglyceridemia 0.840 (0.588,1.201) 1.089 (0.950,1.310) 1.069 (0.881,1.298) 1.190 (0.933,1.517)
1.236 (0.5835,1.830) 1.113 (0.914,1.357) 1.047 (0.851,1.289) 1.118 (0.862,1.451)
Low HDL-C 1.113 (0.785,1.580) 1.058 (0.894,1.251) 1.152 (0.966,1.375) 1.235 (0.986,1.546)
1.246 (0.866,1.793) 1.048 (0.882,1.245) 1.153 (0.962,1.381) 1.153 (0.914,1.455)
Hypertension 0.592 (0.435,0.804)** 1.088 (0.929,1.273) 1.144 (0.965,1.357) 0.990 (0.798,1.229)
0.930 (0.651,1.330) 1.167 (0.973,1.399) 1.093 (0.901,1.327) 0.873 (0.682,1.117)
Hyperglycaemia 0.619 (0.459,0.833)** 0.836 (0.719,0.972)* 1.037 (0.880,1.221) 1.065 (0.864,1.314)
0.826 (0.591,1.154) 0.816 (0.689,1.011) 0.951 (0.790,1.143) 0.985 (0.777,1.248)
Metabolic syndrome 0.631 (0.448,0.888)** 0.945 (0.791,1.132) 1.179 (0.973,1.429) 1.258 (0.994,1.593)
1.054 (0.718,1.547) 1.004 (0.824,1.224) 1.137 (0.919,1.221) 1.238 (0.958,1.600)

*P < 0.05, **P < 0.01.

Model 1, Single-factor analysis.

Model 2, Adjusted for confounding factors (age, ethnicity, education level, occupation, annual income, smoking history, other metabolic factors, etc.).