Table 7.
Comparison in variables with or without treatment of osteoporosis followed by propensity score matching.
| Variable | Control (n = 67) | Treatment (n = 60) | P-value (unpaired t-test) |
|---|---|---|---|
| Age at baseline, yr | 65.0 ± 7.4 | 65.0 ± 6.6 | 0.990 |
| Height, cm | |||
| Baseline | 153.1 ± 4.7 | 153.7 ± 4.8 | 0.449 |
| Follow-up | 150.4 ± 5.4 | 150.1 ± 6.4 | 0.804 |
| Change | −2.7 ± 2.4 | −3.6 ± 3.2 | 0.074 |
| P-value (paired t-test) | < 0.001 | < 0.001 | |
| Weight, kg | |||
| Baseline | 52.9 ± 7.0 | 53.0 ± 4.7 | 0.932 |
| Follow-up | 50.7 ± 7.6 | 51.7 ± 5.8 | 0.430 |
| Change | −2.2 ± 4.3 | −1.3 ± 4.1 | 0.251 |
| P-value (paired t-test) | < 0.001 | 0.018 | |
| BMI, kg/m2 | |||
| Baseline | 22.6 ± 3.3 | 22.4 ± 2.2 | 0.759 |
| Follow-up | 22.5 ± 3.7 | 22.9 ± 3.0 | 0.381 |
| Change | −0.1 ± 1.7 | 0.5 ± 2.0 | 0.04 |
| P-value (paired t-test) | 0.553 | 0.035 | |
| Whole-body BMD, g/cm2 | |||
| Baseline | 0.887 ± 0.09 | 0.853 ± 0.128 | 0.084 |
| Follow-up | 0.917 ± 0.106 | 0.892 ± 0.11 | 0.295 |
| Change | 0.026 ± 0.099 | 0.039 ± 0.10 | 0.438 |
| P-value (paired t-test) | 0.044 | 0.001 | |
| Bone mass, kg | |||
| Baseline | 1.49 ± 0.27 | 1.42 ± 0.26 | 0.087 |
| Follow-up | 1.47 ± 0.26 | 1.45 ± 0.27 | 0.616 |
| Change | −0.02 ± 0.21 | 0.03 ± 0.20 | 0.617 |
| P-value (paired t-test) | 0.428 | 0.246 | |
| Fat mass, kg | |||
| Baseline | 17.6 ± 4.7 | 17.9 ± 3.17 | 0.608 |
| Follow-up | 15.9 ± 4.9 | 16.7 ± 4.1 | 0.366 |
| Change | −1.7 ± 3.2 | −1.2 ± 3.1 | 0.519 |
| P-value (paired t-test) | < 0.001 | 0.003 | |
| ALM, kg | |||
| Baseline | 14.1 ± 1.7 | 14.1 ± 1.4 | 0.917 |
| Follow-up | 13.9 ± 1.7 | 13.9 ± 1.5 | 0.816 |
| Change | −0.2 ± 0.9 | −0.2 ± 0.9 | 0.543 |
| P-value (paired t-test) | 0.300 | 0.265 | |
| LMI, kg/cm2 | |||
| Baseline | 6.03 ± 0.69 | 5.96 ± 0.62 | 0.619 |
| Follow-up | 6.14 ± 0.76 | 6.21 ± 0.76 | 0.611 |
| Change | 0.11 ± 0.44 | 0.25 ± 0.45 | 0.111 |
| P-value (paired t-test) | 0.03 | < 0.001 | |
| T-score of total hip BMD | |||
| Baseline | −1.55 ± 1.06 | −2.04 ± 0.84 | 0.005 |
| Follow-up | −2.24 ± 1.04 | −2.27 ± 0.95 | 0.879 |
| Change | −0.69 ± 0.62 | −0.23 ± 0.50 | < 0.001 |
| P-value (paired t-test) | < 0.001 | 0.001 | |
| T-score of lumbar spine BMD | |||
| Baseline | −1.74 ± 1.19 | −2.48 ± 0.82 | < 0.001 |
| Follow-up | −1.85 ± 1.37 | −1.93 ± 1.27 | 0.726 |
| Change | −0.11 ± 0.81 | 0.55 ± 0.95 | < 0.001 |
| P-value (paired t-test) | 0.273 | < 0.001 |
Values are presented as mean ± standard deviation or number.
BMI, body mass index; BMD, bone mineral density; ALM, appendicular lean mass; LMI, lean mass index.