Table 3.
Haematological parameters in the subchronic toxicity experiment.
| Gender | Control | EPFR (mg/kg) |
Satelite Control | Satelite EPFR1 | ||
|---|---|---|---|---|---|---|
| 100 | 400 | 800 | – | 800 | ||
| Female | ||||||
| RBC (x106/μL) | 8.0 ± 1.19 | 9.0 ± 1.71 | 8.4 ± 1.33 | 7.9 ± 1.14 | 7.87 ± 1.01 | 10.7 ± 3.55 |
| Hb (g/dL) | 13.0 ± 1.13 | 13.8 ± 3.3 | 15.4 ± 0.8 | 13.2 ± 1.24 | 12.2 ± 1.21 | 12.9 ± 0.61 |
| Hct (%) | 46.3 ± 3.10 | 47.1 ± 6.2 | 48.3 ± 3.1 | 50.0 ± 2.0 | 46.2 ± 11.0 | 44.0 ± 9.10 |
| Plt (x105/μL) | 7.88 ± 1.29 | 7.3 ± 1.50 | 5.5 ± 1.51 | 5.8 ± 2.101 | 6.36 ± 1.17 | 7.03 ± 1.74 |
| WBC (x103/μL) | 10.7 ± 6.28 | 12.6 ± 5.3 | 13.6 ± 7.4 | 10.8 ± 6.73 | 9.36 ± 4.08 | 10.70 ± 3.5 |
| Male | ||||||
| RBC (x106/μL) | 7.11 ± 1.18 | 8.6 ± 1.07 | 8.3 ± 1.02 | 7.56 ± 1.96 | 7.44 ± 1.09 | 7.53 ± 1.03 |
| Hb (g/dL) | 14.72 ± 1.2 | 12.9 ± 2.3 | 14.2 ± 1.9 | 14.2 ± 1.04 | 14.0 ± 1.05 | 12.8 ± 0.86 |
| Hct (%) | 43.0 ± 9.00 | 49.1 ± 3.0 | 47.0 ± 8.0 | 48.0 ± 2.03 | 47.0 ± 9.13 | 44.0 ± 10.2 |
| Plt (x105/μL) | 5.61 ± 2.72 | 4.58 ± 1.2 | 6.47 ± 0.8 | 5.89 ± 4.08 | 6.40 ± 1.71 | 5.81 ± 1.47 |
| WBC (x103/μL) | 11.24 ± 7.0 | 10.9 ± 4.3 | 11.7 ± 5.9 | 12.9 ± 10.9 | 9.18 ± 2.49 | 11.1 ± 2.98 |
All values are mean + SEM (n = 5).
EPFR: Extract of P. feei roots.
Satelite EPFR: Administration of the extract was continued for 28 days.
1
Significantly different from the control, p < 0.05.