Fig. 3.

Random-effects multivariable cox proportional hazards model to assess the association of clinical characteristics and initial respiratory support with 60-day mortality in patients who underwent advanced ventilatory support (NIRS and/or IMV), adjusted by the time-period of admission. The hospital was considered as the random intercept (standard deviation = 0.50). To account for the non randomization, we used inverse-probability treatment weighting (IPTW) of propensity scores regarding the initial use of NIRS. We provide the hazard ratio (HR) for 60-day in-hospital mortality and its respective 95% confidence intervals for each variable