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. 2021 Apr 13;4(4):e215718. doi: 10.1001/jamanetworkopen.2021.5718

Table 1. Baseline Characteristics of Living Donor Kidney Transplant Donors and Recipients Included in the Analysisa.

Characteristic All (N = 72 980) Not related (n = 29 806) Related (n = 43 174) P value
Donor characteristics
Age, median (IQR), y 41 (32-50) 44 (35-52) 39 (31-48) <.001
Female sex 43 990 (60) 19 142 (64) 24 848 (58) <.001
Race
White 50 014 (69) 23 081 (77) 26 933 (62) <.001
Black/African American 9499 (13) 2541 (9) 6958 (16)
Hispanic/Latino 9836 (13) 2967 (10) 6869 (16)
Predonation serum creatinine, median (IQR), mg/dL 0.8 (0.7-1.0) 0.8 (0.7-1.0) 0.9 (0.7-1.0) <.001
Recipient characteristics
Age, median (IQR), y 49 (37-58) 50 (40-58) 48 (34-58) <.001
Female sex 28 565 (39) 10 530 (35) 18 035 (42) <.001
Race
White 48 032 (66) 21 111 (71) 26 921 (62) <.001
Black/African American 10 764 (15) 3731 (13) 7033 (16)
Hispanic/Latino 9931 (14) 3172 (11) 6759 (16)
Cause of kidney disease
Diabetes 13 146 (18) 5766 (19) 7380 (17) <.001
Hypertension 10 108 (14) 3995 (13) 6113 (14)
Glomerular disease 16 266 (22) 6557 (22) 9709 (22)
Cystic kidney disease 7130 (10) 4600 (15) 2530 (6)
Other or unknown 26 330 (36) 8888 (30) 17 442 (40)
Panel reactive antibody ≥80% 1520 (2) 601 (2) 919 (2) .30
Diabetes 20 925 (29) 8660 (29) 12 265 (28) .06
Peripheral vascular disease 2929 (4) 1230 (4) 1699 (4) .20
Functional impairment 39 156 (54) 16 990 (57) 22 166 (51) <.001
Pretransplant dialysis
Preemptive (no dialysis) 22 572 (31) 9639 (32) 12 933 (30) <.001
<1 y 8433 (12) 3221 (11) 5212 (12)
≥1 y 20 389 (28) 8750 (29) 11 639 (27)
Not preemptive but time not known 21 586 (30) 8196 (28) 13 390 (31)
Employment status
Employed 23 078 (32) 11 138 (37) 11 940 (28) <.001
Not employed 25 261 (35) 10 406 (35) 14 855 (34)
Unknown or missing 24 641 (34) 8262 (28) 16 379 (38)
Insurance
Private 42 967 (59) 18 565 (63) 24 311 (56) <.001
Medicare 19 373 (27) 7984 (27) 11 389 (26)
Medicaid 2787 (4) 780 (3) 2007 (5)
Other 7853 (11) 2386 (8) 5467 (13)
Other characteristics
ABO-incompatible transplant 883 (1) 452 (2) 431 (1) <.001
Transplant era
2000-2004 23 655 (32) 7577 (25) 16 078 (37) <.001
2005-2009 25 460 (35) 10 342 (35) 15 118 (35)
2010-2014 23 865 (33) 11 887 (40) 11 978 (28)

Abbreviation: IQR, interquartile range.

a

Data are presented as number (percentage) of patients unless otherwise indicated.