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. 2021 Mar 25;9:644901. doi: 10.3389/fcell.2021.644901

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Copyright © 2021 Zhu, Zhang, Huang, Lin, Fan and Ni.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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SLC7A11-dependent mechanism of LX-2 ferroptosis. LX-2 cells were co-transfected with oeTRIM26 and oeSLC7A11 plasmids. (A) Protein expressions of TRIM26 and SLC7A11. (B) Lipid peroxidation level. (C) Glutathione content. (D) Hydroxyproline content. (E) Protein expressions of α-SMA and collagen I. *P < 0.05; **p < 0.01; ***P < 0.001.