Table 1.
Demographic and biochemical characteristics of CAP patients (split by median level of 8-iso-PGF2α).
| Variables | 8-iso-PGF2α < median (110) | 8-iso-PGF2α ≥ median (110) | P |
|---|---|---|---|
| Male, n (%) | 56 (51.0) | 54 (49.0) | 0.254 |
| Age (years) | 55.63 ± 2.77 | 71.55 ± 2.03 | 0.031 |
| BMI | 23.0 ± 0.52 | 22.4 ± 0.77 | 0.354 |
| Systolic pressure (mmHg) | 119.5 ± 2.39 | 125.9 ± 3.22 | 0.214 |
| Diastolic pressure (mmHg) | 74.5 ± 1.54 | 72.4 ± 1.42 | 0.198 |
| WBC (109/L) | 7.67 ± 0.91 | 8.90 ± 0.63 | 0.006 |
| Neutrophil (109/L) | 6.87 ± 1.61 | 7.03 ± 0.58 | 0.002 |
| Lymphocyte (109/L) | 1.96 ± 0.43 | 1.13 ± 0.09 | 0.001 |
| NLR | 5.28 ± 1.13 | 8.07 ± 0.88 | <0.001 |
| MON | 0.33 ± 0.03 | 0.57 ± 0.07 | 0.005 |
| PLR | 205.1 ± 23.06 | 257.6 ± 19.32 | 0.022 |
| ALT (U/L) | 31.90 ± 4.47 | 24.7 ± 3.05 | 0.042 |
| AST (U/L) | 32.33 ± 4.47 | 31.49 ± 3.11 | 0.568 |
| Total bilirubin (umol/L) | 13.31 ± 1.66 | 13.20 ± 1.08 | 0.554 |
| Albumin (g/L) | 35.43 ± 0.93 | 30.66 ± 0.83 | 0.852 |
| Total bile acid (umol/L) | 3.83 ± 0.64 | 4.53 ± 0.77 | 0.479 |
| Urea nitrogen (mmol/L) | 5.56 ± 0.35 | 6.49 ± 0.58 | 0.036 |
| Creatinine (μmol/L) | 61.22 ± 5.14 | 74.82 ± 7.92 | 0.035 |
| Uric acid (μmol/L) | 281.7 ± 12.30 | 276.7 ± 19.53 | 0.059 |
| TNFα (pg/mL) | 549.9 ± 56.30 | 930.3 ± 83.22 | 0.001 |
| IL-1β (pg/mL) | 359.2 ± 32.58 | 593.5 ± 79.33 | 0.013 |
| IL-6 (pg/mL) | 244.4 ± 17.59 | 164.8 ± 52.28 | 0.018 |
| CRP (mg/L) | 38.5 ± 8.51 | 77.9 ± 11.24 | 0.043 |
| CURB-65 | 1.0 (0, 2.0) | 2.0 (1.0, 4.0) | <0.001 |
| CRB-65 | 1.0 (0, 1.75) | 2.0 (1.0, 3.0) | <0.001 |
| PSI | 63.0 (45.0, 96.8) | 123.0 (82.0, 151.0) | <0.001 |
| CURXO [Severe, n (%)] | 29 (26.4) | 45 (40.1) | 0.022 |
| SMART-COP | 1.0 (0, 2.0) | 5.0 (1.0, 7.0) | <0.001 |