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. 2021 Mar 29;11:592842. doi: 10.3389/fcimb.2021.592842

Table 2.

Differences in cognitive scale items between the three groups.

Item/Group NC SCD aMCI P Value
HAMD 0(0–10) 0(0–4) 0(0–20) 0.771
HAMA 0(0–10) 0(0–3) 0(0–34) 0.945
AVLT-H (S) 6.86 ± 1.588 5.27 ± 1.971 4.06 ± 1.798 <1e-04***
AVLT-H (L) 6.61 ± 1.500 4.81 ± 2.191 3.61 ± 1.720 <1e-04***
MoCA-B 25.25 ± 1.720 24.04 ± 2.490 18.50 ± 3.015 <1e-04***
BNT (unit) 3.97 ± 0.167 3.92 ± 0.272 3.39 ± 0.778 <1e-04***
VFT (unit) 17.00 ± 3.171 15.31 ± 3.696 14.00 ± 3.726 0.009**
STT-B (S) 171.97 ± 39.823 173.23 ± 45.921 220.06 ± 58.516 0.004***
CDT30 25.90 ± 2.792 25.65 ± 2.314 21.50 ± 3.974 <1e-04***
ADL 24.17 ± 7.225 24.62 ± 6.735 26.17 ± 9.218 0.374

HAMD, Hamilton's Depression Scale; HAMA, Hamilton's Anxiety Scale; AVLT-H (S), Auditory verbal learning test-Huashan version for short term; AVLT-H (L), Auditory verbal learning test-Huashan version for long term; MoCA-B, Montreal Cognitive Assessment-Basic; BNT, Bonston naming test; VFT, Verbal fluency test; STT-B, Shape trail test B; CDT30, Draw the clock test; ADL, Activity of Daily Living. BNT and VFT’s units were single, STT-B’s unit was second, and the other items’ units were scores. Skewed distribution data, such as depression and anxiety score data, were expressed by median, maximum, and minimum values, and the rest of normal distribution data were expressed by mean plus or minus standard deviation. And we applied non-parametric rank sum test in depression and anxiety score data analysis, and one way ANOVA analysis in the other neuropsychological assessment items. ** shows P < 0.01, *** shows P < 0.005.