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. 2021 Mar 23;11:648528. doi: 10.3389/fonc.2021.648528

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Copyright © 2021 Arzanforoosh, Croal, van Garderen, Smits, Chappell and Warnert

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pre-processing workflow. 1) T₂-weighted (T2W), FLAIR, T₁-weighted precontrast (T1W) and postcontrast (T1W+C) images used for CET and NCET, and NAWM segmentation, 2) Binary mask of CET/NCET (red color) and NAWM (green color) mask on the structural data, 3) Registered Binary mask of CET/NCET on the third volume of DSC-MR imaging. CET, Contrast Enhanced Tumor; NCET, Non Contrast Enhanced Tumor; NAWM, Normal Appearing White Matter.