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. 2021 Mar 31;12:564097. doi: 10.3389/fphar.2021.564097

TABLE 2.

All-cause Mortality and Cancer incidence Between Two Groups After 1:1 propensity score-matching.

Digoxin group n = 758 β-blocker group n = 758 Adjusted hazard ratio (95%CI) p value Subdistribution hazard ratio (95%CI) p value
4-year follow-up
 All-cause mortality 79 (10.4%) 37 (4.9%) 1.74 (1.18–2.59) 0.006 a NA NA
 Cancer incidence 43 (5.7%) 30 (4.0%) 1.26 (0.79–2.02) 0.34 1.99 (1.22–3.01) 0.006 a
8-year follow-up
 All-cause mortality 103 (13.6%) 53 (7.0%) 1.41 (1.01–1.97) 0.046 a NA NA
 Cancer incidence 57 (7.5%) 40 (5.3%) 1.17 (0.78–1.76) 0.45 1.46 (1.01–2.15) 0.054

CCB = calcium channel blocker; CI = confidence interval; Cox proportional hazards regression.

a

p value < 0.05Subdistribution hazards regression.

b

p value < 0.05.