Table 1.
Participant characteristics.
| HIVneg HC | HIVpos INR | HIVpos IT | HIVpos IR | ||
|---|---|---|---|---|---|
| n= | 30 | 23 | 14 | 26 | P-value |
| Median age (range) | 41 (24–50) | 43 (25–50) | 44 (38–48) | 41 (33–49) | *0.511 |
| Median CD4 count (range) | NA | 251 (80–347) | 388 (352–491) | 611 (503–1505) | *<0.0001 |
| Median CD4+ Nadir (range) | NA | 62 (0–255) | 79 (0–203) | 89 (3–249) | *0.91 |
| Gender | 76% male | 77% male | 100% male | 75% male | **0.207 |
| CMV % sero pos | 30.0% | 100% | 100% | 85% | **all grps = <0.0001 HIV+ grps = 0.048 |
| Race | 8% black | 41% black | 50% black | 54% black | |
| 88%white | 55% white | 50% white | 42% white | ||
| 4% Other | 4% Other | 4% Other | |||
| ART regimen | NA | ||||
| NRTI + NNRTI | 61% | 57% | 35% | ||
| NRTI + PI | 30%$ | 36% | 62% | ||
| NRTI + INSTI | 4% | 7%∧ | 4% |
NA, not available; CMV, cytomegalovirus; NRTI, nucleoside reverse transcriptase inhibitors; NNRTI, non-nucleoside reverse transcriptase inhibitors; PI, protease inhibitor; INSTI, integrase strand transfer inhibitor.
HC = uninfected age distribution-matched control (≤50 years old).
INR = immune non-responders; ART treated; <350 CD4 T cells/uL; <50 years old.
IT = intermediate CD4 counts; ART treated; 350–500 CD4 T cells/uL; <50 years old.
IR = immune responders; ART treated; >500 CD4 T cells/uL; <50 years old.
There was no significant difference in age among INR, IT, IR, or HC populations.
*
Kruskal-Wallis;
**
Chi Squared; one patient received PI only; one patient received PI also.