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. 2021 Mar 25;8:635245. doi: 10.3389/fmolb.2021.635245

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Copyright © 2021 Borah, Deb, Al-Shar’i, Dahabiyeh, Venugopala, Singh, Shinu, Hussain, Deka, Chandrasekaran and Jaradat.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Genomic organization of SARS-CoV-2; (A) The structure of SARS-CoV-2 containing spherical crown-like lipid envelope showing structural proteins, namely Spike (S), Envelope (E), Nucleocapsid (N), and Membrane (M) proteins surrounding the non-segmented (+)-sense single stranded RNA encoding for several non-structural proteins (NSPs); (B) The SARS-CoV-2 genome representing the arrangement of - 5′ untranslated region (5′-UTR) caps, ORF1ab (replicase), S, E, M, N, and other genes encoding for the NSPs like ORF 3, 6, 7a, 7b, 8, and 9b; and 3′-UTR (poly-A tails).