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. 2021 Mar 18;9:603361. doi: 10.3389/fped.2021.603361

Table 2.

Comparison between survivors and non-survivors with regard to clinical data and outcome parameters (N = 91).

Variables Mortality P-value
Survivors (N = 72) Non-survivors (N = 19)
Age (months), median (IQR) 7.5 (3.6–30) 10 (3–20) 0.887
Sex, n (%)
Male 39 (54.2%) 8 (42.1%) 0.349
Female 33 (45.8%) 11 (57.9%)
BMI Z score −1.05 (−2.0–1.15) −0.25 (2.0–1.0) 0.692
Diagnoses, n (%)
Respiratory 23 (31.9%) 6 (31.6%) 0.976
CVS 7 (9.7%) 3 (15.8%) 0.452
CNS 11 (15.3%) 3 (15.8%) 0.956
GIT & hepatic 1 (1.4%) 1 (5.3%) 0.306
Sepsis 12 (16.7%) 4 (21.1%) 0.655
Surgical 10 (13.9%) 0.09
Metabolic 5 (6.9%) 0.24
Hematological 1 (1.4%) 1 (5.3%) 0.306
Renal 2 (2.8%) 1 (5.3%) 0.589
PRISM, median (IQR) 3 (2–6) 6 (3–8) 0.039
Fasting insulin (mIU/L/), median (IQR) 5.95 (1.77–10.3) 1.9 (0.53–5) 0.030
HOMA-β % median (IQR) 25.97 (7.05–105.66) 14.52 (6.34–22.25) 0.050
Log HOMA- β (%) Geometric mean (95% CI) 31.37 (19.83–49.62) 12.08 (6.38–22.88) 0.048
HOMA-IR median (IQR) 1.56 (0.64–2.43) 0.68 (0.22–2.24) 0.105
Log Homa-IR Geometric mean (95% CI) 1.1 (0.76–1.58) 0.57 (0.28–1.16) 0.101
CRP (Positive) n (%) 33 (45.8%) 8 (42.1%) 0.771
Inotropic use, n (%) 71 (98.6%) 18 (94.7%) 0.376
PICU stay (days), median (IQR) 4 (3–6) 5 (3–10) 0.226
Hospital stay (days), median (IQR) 5.5 (4–7) 5 (4–10) 0.425
MV (days), median (IQR) 0 (0–4) 2 (1–3) 0.012

MV, mechanical ventilation; PRISM, Pediatric risk of mortality score; CVS, cardiovascular system; CNS, central nervous system; GIT, gastrointestinal tract; IQR, interquartile range.

CI, confidence interval; HOMA-IR, Homeostatic model assessment-Insulin resistance; CRP, C-reactive protein (N < 5 mg/L).

Significant values are indicated in bold.