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. 2021 Mar 19;8:600986. doi: 10.3389/fvets.2021.600986

Table 2.

Common antibodies used for the characterization of B-cells in dogs and expected reactivities.

Target Antibody clones Reactivity
CD18 CA1.4E9 All leukocytes
CD19 4E9 B-cells, including early precursors
CD20 NCD1.2 Mature B-Lymphocytes
1E4
6C8
CD21 CA2.1D6 Mature B-lymphocytes
CD22 RFB4 Mature B-lymphocytes
CD25 P4A10 Activated lymphocytes
CD34 1H6 Precursors
CD45 YKIX716.13 All leukocytes
CA12.10C12
CD44 IM7 All hematopoietic cells
CD79a(cy) HM57 B-cells, including early precursors
CD79b(cy) AT107-2 B-cells, including early precursors
IgM polyclonal Immature/Mature B-cells
MHC II YKIX334.2 Monocytes, Histiocytes, Lymphocytes
CA2.1C12
Ki67 (nuclear) MIB-1 Proliferating cells

cy, cytoplasmic.