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. 2021 Apr 8;7(4):e06683. doi: 10.1016/j.heliyon.2021.e06683

Table 2.

Swiss ADME pharmacokinetics prediction for the compounds BOP-1 and BOP-8.

Compound MW (g/mol) Bioavailability Scorea Solubilityb Log Pc Drug likeness
BOP-1 487.19 0.55 Moderately soluble 4.7 Yes
BOP-8 458.34 0.55 Moderately soluble 4.4 Yes
a

Abbott bioavailability score: probability of F>10% in rat.

b

Solubility class: log S scale.

c

Calculated by XLOGP program version 3.2.2.