Table 1.
Characteristics of patients at admission and comparison regarding condition status
| All patients (n = 57) | Surviving (n = 45) | Dead (n = 12) | p value | ||
|---|---|---|---|---|---|
| Demographic characteristics | |||||
| Male gender (%) | 44 (64) | 11 (24) | 10 (83) | 0.56 | |
| Age (years) | 62 (± 14) | 59 (± 14) | 72 (± 10) | 0.003 | |
| BMI (kg/m2) | 28 (± 6) | 28 (± 6) | 30 (± 6) | 0.23 | |
| Medical history | |||||
| Hypertension (%) | 28 (49) | 20 (44) | 8 (67) | 0.17 | |
| Coronary disease (%) | 10 (15) | 6 (13) | 4 (33) | 0.10 | |
| Chronic heart failure (%) | 5 (7) | 3 (6) | 2 (16) | 0.27 | |
| Diabetes (%) | 22 (32) | 19 (42) | 3 (25) | 0.27 | |
| Smoking (%) | 11 (16) | 7 (19) | 4 (33) | 0.32 | |
| Obesity (%) | 19 (28) | 14 (31) | 5 (42) | 0.49 | |
| Clinical evaluation at admission | |||||
| SAPS II | 36 (± 18) | 35 (± 20) | 42 (± 10) | 0.21 | |
| Time since first symptom (days) | 7 (± 4) | 7 (± 4) | 6 (± 4) | 0.90 | |
| SOFA | 4 (± 3) | 4 (± 3) | 5 (± 3) | 0.20 | |
| SOFA respiratory | 2 (± 1) | 2 (± 1) | 2 (± 1) | 0.72 | |
| MV at admission (%) | 17 (25) | 12 (27) | 5 (42) | 0.31 | |
| PaO2/FiO2 ratio (mmHg) | 172 (± 75) | 181 (± 77) | 134 (± 57) | 0.09 | |
| BNP (pg/ml) | 409 (± 658) | 247 (± 341) | 1339 (± 1241) | 0.001 | |
| Troponin Us (µg/ml) | 38 (± 70) | 28 (± 59) | 76 (± 95) | 0.05 | |
| Lactataemia (mmol/l) | 1.6 (± 0.7) | 1.6 (± 0.7) | 1.6 (± 0.7) | 0.90 | |
| Norepinephrine (mg/h) | 0.3 (± 0.9) | 0.3 (± 1) | 0.3 (± 0.7) | 0.94 | |
| Evolution in ICU | |||||
| Use of MV (%) | 40 (70) | 31 (78) | 9 (75) | 0.68 | |
| Use of prone position (%) | 37 (54) | 27 (60) | 10 (83) | 0.13 | |
| Use of RRT (%) | 9 (13) | 6 (13) | 3 (25) | 0.32 | |
| Use of ECMO (%) | 5 (7) | 4 (8) | 1 (8) | 0.95 | |
| MV-free days | 12 (± 12) | 14 (± 12) | – | ||
| ICU-free days | 8 (± 10) | 10 (± 10) | – | ||
BMI body mass index, BNP brain natriuretic peptide, ECMO extracorporeal membrane oxygenation, ICU intensive care unit, MV mechanical ventilation, RRT renal replacement therapy, SAPS Simplified Acute Physiology Score, SOFA Sequential Organ Failure Assessment