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. 2021 Mar 30;21(6):428. doi: 10.3892/ol.2021.12689

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Copyright: © Lohberger et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Effects of bortezomib and IR on the cell cycle distribution. (A and B) Representative flow cytometry cell cycle measurements (A) at 48 h post-IR exposure and (B) following co-treatment with bortezomib. Cell populations in the G₀/G₁, S and G₂/M phases are presented as the mean percentage of total cells (n=5). IR caused a decrease in the number of cells in G₁ (black) and S (dashed) phase, which was accompanied by a pronounced increase of cells in G₂/M phase (grey) (n=5). IR, ionizing radiation; Ctrl, control; Bor, bortezomib.