Table II.
Association between clinical characteristics of patients with oral squamous cell carcinoma and XRCC1 expression.
| XRCC1 expression | |||
|---|---|---|---|
| Characteristics | Low, n (%) | High, n (%) | P-value |
| Age, years | |||
| <50 | 13 (46.4) | 34 (48.6) | 0.850 |
| ≥50 | 15 (53.6) | 36 (51.4) | |
| Sex | |||
| Male | 28 (100.0) | 64 (91.4) | 0.180a |
| Female | 0 (0.0) | 6 (8.6) | |
| Cigarette smoking | |||
| No | 1 (3.6) | 10 (14.3) | 0.170a |
| Yes | 27 (96.4) | 60 (85.7) | |
| Betel quid chewing | |||
| No | 7 (25.0) | 23 (32.9) | 0.450 |
| Yes | 21 (75.0) | 47 (37.1) | |
| Alcohol consumption | |||
| No | 6 (21.4) | 29 (41.4) | 0.070 |
| Yes | 22 (78.6) | 41 (58.6) | |
| Tumor location | |||
| Buccal mucosa | 24 (85.7) | 52 (74.3) | 0.290a |
| Tongue | 4 (14.3) | 18 (25.7) | |
| Grade | |||
| Grade I | 26 (92.9) | 60 (85.7) | 0.500a |
| Grade II+III | 2 (7.1) | 10 (14.3) | |
| Tumor size | |||
| T1+T2 | 16 (57.1) | 36 (51.4) | 0.610 |
| T3+T4 | 12 (42.9) | 34 (48.6) | |
| Lymph node metastases | |||
| N0 | 15 (53.6) | 35 (50.0) | 0.750 |
| N1+N2 | 13 (46.4) | 35 (50.0) | |
| Tumor stage | |||
| I+II | 11 (39.3) | 24 (34.3) | 0.640 |
| III+IV | 17 (60.7) | 46 (65.7) | |
| Radiotherapy | |||
| No | 18 (64.3) | 35 (50.0) | 0.200 |
| Yes | 10 (35.7) | 35 (50.0) | |
| Chemotherapy | |||
| No | 12 (42.9) | 24 (34.3) | 0.430 |
| Yes | 16 (57.1) | 46 (65.7) | |
| Recurrence | |||
| No | 13 (46.4) | 16 (22.9) | 0.020 |
| Yes | 15 (53.6) | 54 (77.1) | |
a
Analyzed using Fisher's exact test. XRCC1, X-ray repair cross-complementing group 1.