Table III.
Association between clinical characteristics of patients with oral squamous cell carcinoma and ERCC1 expression.
| ERCC1 expression | |||
|---|---|---|---|
| Characteristics | Low, n (%) | High, n (%) | P-value |
| Age, years | |||
| <50 | 19 (47.5) | 28 (48.3) | 0.940 |
| ≥50 | 21 (52.5) | 30 (51.7) | |
| Sex | |||
| Male | 36 (90.0) | 56 (96.6) | 0.220a |
| Female | 4 (10.0) | 2 (3.4) | |
| Smoking | |||
| No | 4 (10.0) | 7 (12.1) | >0.999a |
| Yes | 36 (90.0) | 51 (87.9) | |
| Betel quid chewing | |||
| No | 11 (27.5) | 19 (32.8) | 0.580 |
| Yes | 29 (72.5) | 39 (67.2) | |
| Alcohol consumption | |||
| No | 14 (35.0) | 21 (36.2) | 0.900 |
| Yes | 26 (65.0) | 37 (63.8) | |
| Tumor location | |||
| Buccal mucosa | 32 (80.0) | 44 (75.9) | 0.630 |
| Tongue | 8 (20.0) | 14 (24.1) | |
| Grade | |||
| Grade I | 35 (87.5) | 51 (87.9) | >0.999 |
| Grade II+III | 5 (12.5) | 7 (12.1) | |
| Tumor size | |||
| T1+T2 | 22 (55.0) | 30 (51.7) | 0.750 |
| T3+T4 | 18 (45.0) | 28 (48.3) | |
| Lymph node metastases | |||
| N0 | 22 (55.0) | 28 (48.3) | 0.510 |
| N1+N2 | 18 (45.0) | 30 (51.7 | |
| Tumor stage | |||
| I+II | 15 (37.5) | 20 (34.5) | 0.760 |
| III+IV | 25 (62.5) | 38 (65.5) | |
| Radiotherapy | |||
| No | 23 (57.5) | 30 (51.7) | 0.680 |
| Yes | 17 (42.5) | 28 (48.3) | |
| Chemotherapy | |||
| No | 17 (42.5) | 19 (32.8) | 0.330 |
| Yes | 23 (57.5) | 39 (67.2) | |
| Recurrence | |||
| No | 18 (45.0) | 11 (19.0) | 0.006 |
| Yes | 22 (55.0) | 47 (81.0) | |
a
Analyzed using Fisher's exact test. ERCC1, excision repair cross-complementing group 1.