Table IV.
Association between clinical characteristics of patients with oral squamous cell carcinoma and ERCC2 expression.
| ERCC2 expression | |||
|---|---|---|---|
| Characteristics | Low, n (%) | High, n (%) | P-value |
| Age, years | |||
| <50 | 21 (53.8) | 26 (44.1) | 0.340 |
| ≥50 | 18 (46.2) | 33 (55.9) | |
| Sex | |||
| Male | 36 (92.3) | 56 (94.9) | 0.680a |
| Female | 3 (7.7) | 3 (5.1) | |
| Smoking | |||
| No | 5 (12.8) | 6 (10.2) | 0.680 |
| Yes | 34 (87.2) | 53 (89.8) | |
| Betel quid chewing | |||
| No | 8 (20.5) | 22 (37.3) | 0.080 |
| Yes | 31 (79.5) | 37 (62.7) | |
| Alcohol consumption | |||
| No | 12 (30.8) | 23 (39.0) | 0.410 |
| Yes | 27 (39.2) | 36 (61.0) | |
| Tumor location | |||
| Buccal mucosa | 28 (71.8) | 48 (81.4) | 0.270 |
| Tongue | 11 (28.2) | 11 (18.6) | |
| Grade | |||
| Grade I | 34 (87.2) | 52 (88.1) | >0.999 |
| Grade II+III | 5 (12.8) | 7 (11.9) | |
| Tumor size | |||
| T1+T2 | 24 (61.5) | 28 (47.5) | 0.170 |
| T3+T4 | 15 (38.5) | 31 (52.5) | |
| Lymph node metastases | |||
| N0 | 24 (61.5) | 26 (44.1) | 0.090 |
| N1+N2 | 15 (38.5) | 33 (55.9) | |
| Tumor stage | |||
| I+II | 18 (46.2) | 17 (28.8) | 0.080 |
| III+IV | 21 (53.8) | 42 (71.2) | |
| Radiotherapy | |||
| No | 20 (51.3) | 33 (55.9) | 0.650 |
| Yes | 19 (48.7) | 26 (44.1) | |
| Chemotherapy | |||
| No | 18 (46.2) | 18 (30.5) | 0.120 |
| Yes | 21 (53.8) | 41 (69.5) | |
| Recurrence | |||
| No | 23 (59.0) | 6 (10.2) | <0.001 |
| Yes | 16 (41.0) | 53 (89.8) | |
a
Analyzed using Fisher's exact test. ERCC2, excision repair cross-complementing group 2.