Table V.

Univariate and multivariate analyses of recurrence predictors in 98 patients with oral squamous cell carcinoma.

	Recurrence		Univariate analysis	Multivariate analysis
Characteristics	Yes	No	P-value	Hazard ratio (95% CI)	P-value
Age, years
≥50	32 (46.4)	19 (65.5)	0.080	1.0	0.370
<50	37 (53.6)	10 (34.5)		1.28 (0.75–2.20)
Sex
Female	3 (4.3)	3 (10.3)	0.360	1.0	0.290
Male	66 (95.7)	26 (89.7)		0.48 (0.13–1.83)
Smoking
No	8 (11.6)	3 (10.3)	>0.999	1.0	0.400
Yes	61 (88.4)	26 (89.1)		0.64 (0.22–1.84)
Betel quid chewing
No	23 (33.3)	7 (24.1)	0.370	1.0	0.330
Yes	46 (66.7)	22 (75.9)		1.39 (0.72–2.71)
Alcohol consumption
No	27 (39.1)	8 (27.6)	0.370	1.0	0.960
Yes	42 (60.9)	21 (72.4)		0.98 (0.54–1.81)
Tumor location
Buccal mucosa	53 (76.8)	23 (79.3)	0.790	1.0	0.190
Tongue	16 (23.2)	6 (20.7)		0.64 (0.32–1.25)
Grade
Grade I	60 (87.0)	26 (89.7)	>0.999	1.0	0.680
Grade II+III	9 (13.0)	3 (10.3)		0.86 (0.40–1.81)
Tumor size
T1+T2	34 (49.3)	18 (62.1)	0.250	1.0	0.150
T3+T4	35 (50.7)	11 (37.9)		1.78 (0.81–3.88)
Lymph node metastases
N0	29 (42)	21 (72.4)	0.006	1.0	0.045
N1+N2	40 (58)	8 (27.6)		2.38 (1.02–5.58)
Tumor stage
I+II	21 (30.4)	14 (48.3)	0.090	1.0	0.460
III+IV	48 (69.6)	15 (51.7)		0.65 (0.20–1.71)
XRCC1 expression
Low	15 (21.7)	13 (44.8)	0.020	1.0	0.450
High	54 (78.3)	16 (55.2)		1.31 (0.65–2.66)
ERCC1 expression
Low	22 (31.9)	18 (62.1)	0.006	1.0	0.460
High	47 (68.1)	11 (37.9)		1.25 (0.69–2.25)
ERCC2 expression
Low	16 (23.2)	23 (79.3)	<0.001	1.0	<0.001
High	53 (76.8)	6 (20.7)		4.84 (2.56–9.16)

XRCC1, X-ray repair cross-complementing group 1; ERCC1/2, excision repair cross-complementing group 1/2.