Table VI.

Univariate and multivariate analysis of survival predictors in 98 patients with oral squamous cell carcinoma.

	Death		Univariate analysis	Multivariate analysis
Characteristics	Yes	No	P-value	Hazard ratio (95% CI)	P-value
Age, years
≥50	25 (54.3)	26 (50.0)	0.540	0.96 (0.48–19.2)	0.910
<50	21 (45.7)	26 (50.0)		1
Sex
Female	3 (6.5)	3 (5.8)	0.410	1	0.290
Male	43 (93.5)	49 (94.2)		0.43 (0.09–2.04)
Smoking
No	5 (10.9)	6 (11.5)	0.880	1	0.350
Yes	41 (89.1)	46 (88.5)		0.53 (0.14–2.00)
Betel quid chewing
No	19 (41.3)	15 (28.8)	0.270	1	0.790
Yes	27 (58.7)	37 (71.2)		1.11 (0.53–2.32)
Alcohol consumption
No	17 (37.0)	18 (34.6)	0.910	1	0.460
Yes	29 (63.0)	34 (65.4)		1.33 (0.62–2.86)
Tumor location
Buccal mucosa	39 (84.8)	37 (71.2)	0.060	1	0.010
Tongue	7 (15.2)	15 (28.8)		4.11(1.39–12.14)
Grade
Grade I	38 (82.6)	48 (92.3)	0.710	1	0.430
Grade II+III	8 (17.4)	4 (7.7)		0.71 (0.30–1.67)
Tumor size
T1+T2	17 (37.0)	35 (37.3)	0.001	1	0.430
T3+T4	29 (63.0)	17 (32.7)		1.55 (0.52–4.58)
Lymph node metastases
N0	29 (63.0)	19 (36.5)	0.005	1	0.560
N1+N2	17 (37.0)	33 (63.5)		1.31 (0.54–31.8)
Tumor stage
I+II	9 (19.6)	26 (50.0)	0.001	1	0.500
III+IV	37 (80.4)	26 (50.0)		1.70 (0.36–8.04)
XRCC1 expression
Low	5 (10.9)	23 (44.2)	0.002	1	0.100
High	41 (89.1)	29 (41.4)		2.65 (0.82–8.52)
ERCC1 expression
Low	10 (21.7)	30 (57.7)	0.014	1	0.900
High	36 (78.3)	22 (42.3)		1.06 (0.45–2.50)
ERCC2 expression
Low	3 (6.5)	36 (69.2)	<0.001	1	<0.001
High	43 (93.5)	16 (60.2)		15.55 (4.34–55.67)

XRCC1, X-ray repair cross-complementing group 1; ERCC1/2, excision repair cross-complementing group 1/2.