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Affinity of TRAIL-Mu3 to PANC-1 cell membranes is significantly enhanced. (A) Cell nuclei were stained with Hoechst 33342 (blue) and cell membranes were stained with DiI (red). TRAIL-Mu3 or TRAIL were labeled with FITC (green). Scale bar, 20 µm. (B) Quantification of the signal expressed as a ratio of TRAIL- or TRAIL-Mu3-positive cells to nuclei number. *P<0.001 vs. TRAIL. TRAIL-Mu3, recombinant TNF-related apoptosis-inducing ligand.
