Table I.
Association between LEMD1 expression and clinicopathological features in The Cancer Genome Atlas cohort (n=502).
| High LEMD1 | Low LEMD1 | |||
|---|---|---|---|---|
| Clinicopathological features | expression (n=251) | expression (n=251) | χ2 | P-value |
| Histological type | 30.288 | <0.001a | ||
| Classical | 206 | 150 | ||
| Other types | 45 | 101 | ||
| Age, years | <0.001 | >0.999a | ||
| Mean ± SD | 47.55±16.03 | 47.13±15.66 | ||
| ≤45 | 113 | 113 | ||
| >45 | 138 | 138 | ||
| Sex | 0.010 | 0.920a | ||
| Male | 67 | 68 | ||
| Female | 184 | 183 | ||
| Tumor size, mm | 4.277 | 0.039a | ||
| ≥20 | 189 | 168 | ||
| <20 | 62 | 83 | ||
| Lymph node metastasis | 35.179 | <0.001a | ||
| Yes | 144 | 78 | ||
| No | 107 | 173 | ||
| Distant metastasis | NA | 0.504b | ||
| Yes | 3 | 6 | ||
| No | 248 | 245 | ||
| AJCC disease stage | 10.992 | 0.001a | ||
| I+II | 150 | 185 | ||
| III+IV | 101 | 66 |
a
χ2 test.
b
Fisher's exact test. LEMD1, LEM domain containing 1; AJCC, American Joint Committee on Cancer; NA, not applicable.