Table II.
Association between LEMD1 expression and clinicopathological features in the local validated cohort (n=47).
| High LEMD1 | Low LEMD1 | |||
|---|---|---|---|---|
| Clinicopathological features | expression (n=23) | expression (n=24) | χ2 | P-value |
| Histological type | NA | NA | ||
| Classical | 23 | 24 | ||
| Age, years | 0.180 | 0.671a | ||
| Mean ± SD | 47.56±14.43 | 48.23±14.86 | ||
| ≤45 | 15 | 14 | ||
| >45 | 11 | 10 | ||
| Sex | 0.295 | 0.587a | ||
| Male | 6 | 8 | ||
| Female | 17 | 16 | ||
| Tumor size, mm | 0.236 | 0.627a | ||
| ≥20 | 15 | 14 | ||
| <20 | 8 | 10 | ||
| Lymph node metastasis | 7.671 | 0.006a | ||
| Yes | 16 | 7 | ||
| No | 7 | 17 | ||
| Distant metastasis | NA | NA | ||
| No | 23 | 24 | ||
| AJCC disease stage | NA | 0.002b | ||
| I+II | 15 | 24 | ||
| III+IV | 8 | 0 |
χ2 test.
Fisher's exact test. LEMD1, LEM domain containing 1; AJCC, American Joint Committee on Cancer; NA, not applicable.