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JUN functions as a key TF that associated with the development of OA. a A subnetwork of the first-neighbored genes with JUN. b The expression level of genes in the subnetwork in (a). Values represent mean ± s.d. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001 by Student’s t test. c Gene ontology for putative target genes of JUN. “MAGeCKFlute” R package was applied to perform the enrichment analysis
