Table2.
Characteristics of patients according to CFP score
| Variables | Low CFP group | High CFP group | p value |
|---|---|---|---|
| Gender | 0.729 | ||
| Male | 68 (71.6) | 32 (74.4) | |
| Female | 27 (28.4) | 11 (25.6) | |
| Age, years [median (CI)] | 60 (58–63) | 60 (56–64) | 0.899 |
| Site | 0.076 | ||
| Low | 35 (36.8) | 8 (18.6) | |
| Middle | 46 (48.4) | 28 (67.4) | |
| Upper | 14 (14.7) | 6 (14.0) | |
| Tumor size | 0.002 | ||
| > 5 cm | 35 (36.8) | 28 (65.1) | |
| ≤ 5 cm | 60 (63.2) | 15 (34.9) | |
| ypTNM category | < 0.001 | ||
| 0-I | 62 (65.3) | 12 (27.9) | |
| II-III | 33 (34.7) | 31 (72.1) | |
| Histopathology (N = 129) | 0.335 | ||
| Well differentiation | 5 (5.8) | 1 (2.3) | |
| Moderate differentiation | 74 (86.0) | 35 (81.4) | |
| Poor differentiation | 7 (8.1) | 7 (16.3) | |
| LNH | 8.3 (7.3–9.4) | 10.0 (8.6–11.5) | 0.051 |
| LVI | 0.428 | ||
| Positive | 4 (4.2) | 4 (9.3) | |
| Negative | 91 (95.8) | 39 (90.7) | |
| PNI | < 0.001 | ||
| Positve | 5 (5.3) | 12 (27.9) | |
| Negative | 90 (94.7) | 31 (72.1) | |
| Tumor deposits | 0.148 | ||
| Positive | 11 (11.6) | 9 (20.9) | |
| Negative | 84 (88.4) | 34 (79.1) | |
| TRG | 0.001 | ||
| 0–1 | 64 (67.4) | 16 (37.2) | |
| 2–3 | 31(32.6) | 27 (62.8) | |
| CEA [median (CI)] | 2.6 (2.4–2.9) | 5.3 (3.9–7.1) | 0.002 |
| FARI, % [median(CI)] | 7.0 (6.8–7.3) | 9.3 (8.7–9.9) | < 0.001 |
| PNI [median (CI)] | 47.4 (46.8–48.0) | 42.5 (41.4–43.5) | < 0.001 |
CI confidence interval, LNH lymph node harvest, LVI lymphovascular invasion, PNI perineural invasion, TRG tumor regression grade, CEA carcinoembryonic antigen, FARI Fibrinogen–Albumin Ratio Index, PNI prognostic nutritional index