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. 2021 Apr 14;21:402. doi: 10.1186/s12885-021-08067-1

Table 3.

Clinical measurements for SPN patients from index date by subsequent clinic visit

Visit Characteristics Patients with SPN and no diagnosis of Lung Cancer Visit one following index visit Visit two following index visit Visit three following index visit Visit 4 + all visits up to end of study period
N = 15,978 N = 14,366 N = 13,009 N = 11,715 N = 10,476
Days (median (IQR)) between visits 11 (3, 42) 16 (4, 50) 17 (5, 49) 32.5 (19.3, 56.1)
Cumulative days from index visit (median (IQR)) 11 (3, 42) 38 (12, 104) 67 (25, 151) 196.4 (148.6, 251.5)
LDCT scan 26 (0.16) 4 (0.03) 3 (0.02) 3 (0.03) 6 (0.06)
Chest Imaging 9874 (61.80) 4868 (33.89) 3623 (27.85) 2931 (25.02) 5717 (54.57)
E&M 6129 (38.36) 9632 (67.05) 9483 (72.90) 8886 (75.85) 9972 (95.19)
EBUS/mediastinoscopy 28 (0.18) 34 (0.24) 23 (0.18) 25 (0.21) 75 (0.72)
Biopsya 187 (1.17) 157 (1.09) 143 (1.10) 96 (0.82) 399 (3.81)
PET CT 99 (0.62) 101 (0.70) 100 (0.77) 62 (0.53) 284 (2.71)
Brain MRI 104 (0.65) 148 (1.03) 107 (0.82) 95 (0.81) 576 (5.50)
Bone scan 7 (0.04) 12 (0.08) 21 (0.16) 15 (0.13) 77 (0.74)
SPN diagnosis 15,978 (100.00) 3597 (25.04) 2432 (18.69) 1818 (15.52) 3558 (33.96)
Loss to follow up, N (%)b 1612 (10.09) 1357 (8.49) 1294 (8.10) 1239 (7.75)

abiopsies do not include EBUS/mediastinoscopy

b% relative to the total number of cancer patients (N = 15,978)