Table 3.
CDKN2AB-AS1 quantification in cancer patients as a diagnostic and prognostic biomarker.
Data source: Lnc2Cancer version 2.0
| Cancer type | Methods | Expression pattern | PubMed ID |
|---|---|---|---|
| Circulatory diagnostic biomarker | |||
| Breast cancer | Microarray, qPCR | Up-regulated | 28248879 |
| Intraductal Papillary Mucinous Neoplasms of the Pancreas | qPCR | Up-regulated | 28874676 |
| Acute lymphoblastic leukemia | MassARRAY assay | Up-regulated | 21414664 |
| Neurofibromatosis type 1 | Microarray, qPCR | Up-regulated | 22034633 |
| Non-small cell lung cancer | qPCR | Up-regulated | 29504701 |
| Oral cancer | qPCR, a Luciferase reporter assay, in vitro knockdown | Up-regulated | 29635126 |
| Prognostic biomarker | |||
| Breast cancer | Microarray, qPCR | Up-regulated | 28248879 |
| Triple-negative breast cancer | qPCR, Luciferase reporter assay, RIP | Up-regulated | 28961506 |
| Non-small cell lung cancer | qPCR | Up-regulated | 29504701 |
| Oral cancer | qPCR, a Luciferase reporter assay, in vitro knockdown | Up-regulated | 29635126 |
| Gastric cancer | qPCR, RNAi | Up-regulated | 27121324 |
| Lung adenocarcinoma | qPCR, Western blot | Up-regulated | 28402932 |
| Bladder cancer | qPCR, RNAi, Western blot | Up-regulated | 26800519 |
| Cervical cancer | qPCR, RNAi, Western blot, Cell proliferation assay | Up-regulated | 27899255 |
| Colorectal cancer | qPCR, RNAi, Western blot, Northern blot | Up-regulated | 27286457 |
| Colorectal cancer | qPCR, RNAi | Up-regulated | 27314206 |
| Esophageal squamous cell cancer | qPCR, RNAi, Western blot | Up-regulated | 24747824 |
| Gallbladder cancer | qPCR, Western blot | Down-regulated | 26812694 |
| Gastric cancer | qPCR, RNAi, Western blot, RIP | Up-regulated | 24810364 |
| Gastric cancer | qPCR, RNAi, Western blot, a Luciferase reporter assay, Cell proliferation assay | Up-regulated | 27027260 |
| Glioblastoma | qPCR | Up-regulated | 23046790 |
| Hepatocellular carcinoma | qPCR, Western blot | Up-regulated | 29029488 |
| Hepatocellular carcinoma | qPCR, RNAi | Up-regulated | 26045820 |
| Lung cancer | qPCR, RNAi, Western blot, Cell apoptosis assay | Up-regulated | 25964559 |
| Nasopharyngeal cancer | RT-qPCR, Western blot, a Luciferase reporter assay, in vitro knockdown, RIP | Up-regulated | 29463902 |
| Nasopharyngeal cancer | qPCR, RNAi, Western blot, MTT assay | Up-regulated | 27557514 |
| Non-small cell lung cancer | qPCR, RNAi, Western blot, Luciferase reporter assay | Up-regulated | 27307748 |
| Non-small cell lung cancer | qPCR, RNAi, Cell proliferation assay | Up-regulated | 25889788 |
| Non-small cell lung cancer | qPCR, Western blot | Up-regulated | 25504755 |
| Osteosarcoma | qRT-PCR, Western blot, in vitro knockdown | Up-regulated | 29520337 |
| Ovarian cancer | qPCR, Western blot | Up-regulated | 27095571 |
| Pancreatic cancer | qPCR, Cell transfection, Western blot, cell migration, and invasion assay | Up-regulated | 28344092 |
| Renal cell carcinoma | qPCR, RNAi, Western blot, Cell migration and invasion assay, CCK-8 assay | Up-regulated | 28251886 |
| Serous ovarian cancer | qPCR, RNAi, Western blot | Up-regulated | 25845387 |
| Thyroid cancer | qPCR, RNAi, Western blot | Up-regulated | 27507052 |
Breast cancer-related articles are shown in bold