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. 2021 Apr 14;16:260. doi: 10.1186/s13018-021-02381-x

Table 2.

The diagnostic values of the four tests detecting an ACL ruptures

Items MADT ADT LT PST
True-positive, n 131 95 117 91
True-negative, n 237 235 225 243
False-positive, n 15 17 27 9
False-negative, n 17 53 31 57
Sensitivity (%)a 88.5a 64.2 79.1 61.5
Specificity (%) 94 93.2 89.3 97.2
Accuracy (%)b 92 82.5 85.5 83.5
PPV (%) 89.7 84.8 81.3 91
NPV (%) 93.3 81.6 87.9 81
PLR 14.75 9.44 7.39 21.96
NLR 0.12 0.38 0.23 0.4
DORc 122.92 24.84 32.13 55.45
AUC (mean ± SD)d 0.925 ± 0.014 0.787 ± 0.021 0.842 ± 0.019 0.778 ± 0.021

PPV positive predictive value, NPV negative predictive value, PLR positive likelihood ratio, NLR negative likelihood ratio, DOR diagnostic odds ratio, AUC area under the curve, SD standard deviation, ADT anterior drawer test, LT Lachman test, PST pivot shift test

aThe sensitivity of the MADT was significantly better than ADT (χ2 = 24.249, p < 0.001), LT (χ2 = 4.874, p = 0.027), and PST (χ2 = 22.829, p < 0.001)

bThe accuracy of MADT was significantly higher than ADT (χ2 = 16.226, p < 0.001), LT (χ2 = 8.463, p = 0.004), and PST (χ2 = 13.443, p < 0.001)

cThe diagnosis odds ratio (DOR) of MADT was 122.92, with ADT, LT, and PST were 24.84, 32.13, and 55.45

dThe AUC of the MADT was significantly larger than that of the ADT (z = 5.348, p < 0.001), LTs (z = 3.435, p < 0.001), and PST (z = 5.699, p < 0.001)