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. 2021 Apr 13;22:106. doi: 10.1186/s12931-021-01697-w

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Heatmap depicting the mean delta C_t (ΔC_t) values of antimicrobial resistance and host inflammatory gene expressions from patient sinus swab samples in this study. Elevated expressions of genes, and therefore lower ΔC_t values are noted in blue colours, and lower expressions of genes are noted in red. Mean ΔC_t values were obtained by calculating the differences between endogenous control genes (18S, GAPDH, HPRT1) and genes of interest. Only those genes which were detected in at least one sample are shown. Samples with no gene expression are shaded in grey. All patient baseline samples and P04 left and right samples 7 months after baseline were excluded from gene expression analyses. Mean_DCt = mean ΔC_t, P = Patient, L = left middle meatus, R = right middle meatus. Months from baseline samples are shown preceding sample side L/R