Table 1.

Demographic and clinical data collected from the four patients in this study

Patient	Collection timepointa	Sample collection procedure	Ageb	Sex	Smoker	Ethnicity	CF diagnostic criteria	Age at CF diagnosis	Age at CRS diagnosis	Lung transplant	Nasal polyposis	Lund-Mackay
P01	Baseline	FHFESS	21	M	No	NZE	Δf508	< 5	11	No	Yes	21
	6	Clinic
	13	Clinic
	15	Clinic
	18	FHFESS—revision
P02	Baseline	FHFESS	36	F	No	NZE	Δf508	< 5	Unknown	No	Yes	12
	2	Clinic
	6	Clinic
	11	Clinic
P03	Baseline	FHFESS	50	F	Ex	Maori	Positive sweat tests, no CFTR mutation on genotypingc	> 18	42	No	Yes	13
	3	Clinic
	6	Clinic
	12	Clinic
P04	Baseline	FHFESS—revision	31	F	No	NZE	Δf508	< 5	21	2012	Yes	19
	3	Clinic
	6	Clinic
	7	FHFESS—revision
	11	Clinic

CF cystic fibrosis, CRS chronic rhinosinusitis, FHFESS full house functional endoscopic sinus surgery, NZE New Zealand European

^aCollection timepoint refers to months from baseline sample collection

^bAge at baseline sample collection

^cFulfils diagnostic criteria on the grounds of appropriate phenotypic features (chronic sinopulmonary disease) and laboratory evidence of CFTR dysfunction (sweat chloride > 60 mmol/L on two separate occasions)